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126,127 Glucocorticoid resistance in COPD patients may also be related to the p38MAPK pathway through phosphorylated glucocorticoid receptor (GR) reducing GR translocation into the nucleus and DNA binding, impairing the GR function

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For patients on BPC-157 for joint inflammation, the second and third month often mark the point where the inflammatory pattern breaks rather than just being suppressed

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Zhang, H